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Comparison of two drugs buprenorphine and dexmedetomedine given intrathecally in pregnant patients undergoing caesarean section.

Comparison between intrathecal buprenorphine versus dexmedetomidine with hyperbaric Ropivacaine 0.75% in patients undergoing caesarean section.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/044572
Enrollment
90
Registered
2022-08-02
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services Health Condition 2: O295- Other complications of spinal andepidural anesthesia during pregnancy

Interventions

Intervention1: study of buprenorphine and dexmeditomedine with hyperbaric Ropivacaine: to compare intrathecal buprenorphine 60mcg versus dexmeditomedine 10mcg with hyperbaric Ropivacaineo.75% 15mg in

Sponsors

ESIC Medical College Gulbarga
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Parturients with 1.Singleton pregnancy, scheduled for elective caesarean section under spinal anaesthesia 2.More than 36 weeks of gestation age 3.18-40 years of age 4.Height between 140cm and 180cm 5.BMI less than 32kg/m2, 6.Nil per oral for more than 6 hours

Exclusion criteria

Exclusion criteria: 1.Multiple pregnancy 2.Morbid Obesity (BMI >40) 3.Height 170cms 4.Patients with spinal deformities and those who have undergone previous spine surgeries. 5.Pregnancy related hypertensive disease, preeclampsia, eclampsia. 6.Cardiovascular disease 7.Gestational diabetes requiring insulin. 8.Emergency caesarean sections for maternal or foetal distress. 9.Contraindication to spinal anesthesia.

Design outcomes

Primary

MeasureTime frame
1. To study the onset time and duration of sensory and motor block. 2. To know the time of first analgesic used. 3. To assess post-operative pain scores based on visual analog scale (VAS) at 2 hours, 6 hours and 12 hours after the surgery. Timepoint: 1. To study the onset time and duration of sensory and motor block in pregnant patients who receive the study drug. 2. To know the time of first analgesic used. 3. To assess post-operative pain scores based on visual analog scale (VAS) at 2 hours, 6 hours and 12 hours after the surgery.—

Secondary

MeasureTime frame
1. To study hemodynamic parameters. 2. Side effects like hypotension, bradycardia, shivering, vomiting. Timepoint: 1. To study hemodynamic parameters till the end of surgery. 2. Side effects like hypotension, bradycardia, shivering, vomiting during the surgery and postoperative period.—

Countries

India

Contacts

Public ContactDr Priyanka Y Kanni

ESIC MEDICAL COLLEGE, GULBARGA

priyankakanni@gmail.com9908290999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026