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A study to understand the problems faced by infants of birth weight less than 1500 grams in their childhood.

Survival with disability of very low birth weight infants in first 3 years of life- A retrospective cohort study from a developing country

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/08/044552
Enrollment
1688
Registered
2022-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P073- Preterm [premature] newborn [other]

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Institute of Post Graduate Medical Education and Research Department of Neonatology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Very low birth weight infants (birth weight <1500 g) admitted in the neonatology unit of IPGME&R, Kolkata from January 2016 to December 2020.

Exclusion criteria

Exclusion criteria: 1. VLBW infants with any major congenital malformation (cardiovascular, gastrointestinal, neurological, renal etc.) 2. Infants with suspected chromosomal anomaly, genetic syndromes or metabolic disorders

Design outcomes

Primary

MeasureTime frame
To determine the prevalence of ââ?¬Å?survival with severe disabilityââ?¬? in VLBW infants. Severe disability will be present if any of the following criteria satisfies: 1.Weight -3SD below mean for age and sex or Length -3SD below mean for age and sex or Weight for length -3SD below mean for age and sex as per WHO MGRS chart 2.Microcephaly OFC -3SD below mean for age and sex 3.DMeQ( developmental mental quotient) or DMoQ( developmental motor quotient) 70 in DASII Or Composite cognition or motor score 70 in BSID -III 4. Binocular or monocular acuity in TAC-II( teller acuity card-2nd edition) 99% lower prediction limit for age 5.Cerebral palsy with severe motor impairment (GMFCS level IV or V) 6.Profound to severe hearing loss Timepoint: 1. 18 -24 months corrected age 2. 36 months corrected age

Secondary

MeasureTime frame
1.prevalence of ââ?¬Å?survival with moderate disabilityââ?¬? in VLBW infants 2.prevalence of ââ?¬Å?survival with any disabilityââ?¬? in VLBW infants 3.prevalence of growth failure, microcephaly, motor impairment, developmental delay in VLBW infants 4.prevalence of visual impairment, refractive error, strabismus or cortical visual impairment (CVI) in VLBW infants 5.difference in outcome between SFD and AFD VLBW infants 6.difference in outcome between singleton and multiple gestation 7.difference in outcome between infants with birth weight ââ?°Â¤1000g and more than 1000 g Timepoint: 1. 18 -24 months corrected age 2. 36 months corrected age

Countries

India

Contacts

Public ContactSomnath pal

Institute of Post Graduate Medical Education and Research

somnathpal1983@gmail.com9903457386

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026