to compare effects of lidocaine and dexmedetomidine in controlling hemodynamic and airway responses during the extubation following total thyroidectomy surgery

Efficacy of lidocaine and dexmedetomidine as an adjuvant in attenuating hemodynamic and airway responses during the extubation following total thyroidectomy: A randomised, double blind study.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044490

Enrollment

Registered

2022-07-29

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C73- Malignant neoplasm of thyroid gland

Interventions

Intervention1: LIGNOCAINE: INTRAVENOUS ROUTE DOSE- IV BOLUS LIGNOCAINE 2% 0.5 MG/KG OVER 10 MINS FOLLOWED BY CONTINOUS INFUSION OF 0.5MG/KG/HR TILL 30 MINS BEFORE END OF SURGERY Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: AGE- 18 TO 65 YEARS PATIENTS GIVING CONSENT PATIENTS UNDERGOING THYROIDECTOMY

Exclusion criteria

Exclusion criteria: PATIENTS ALLERGIC TO STUDY DRUGS PATIENTS ON BETA BLOCKER AND ANTI ARRTHYMIC DRUGS

Design outcomes

Primary

Measure	Time frame
HEMODYNAMIC STATUS INTRAOPERATIVELYTimepoint: 6 HRS	—

Secondary

Measure	Time frame
COUGH GRADE AND EASE OF LARYNGOSCOPY TO CHECK MOBILITY OF VOCAL CORDS POST SURGERYTimepoint: 6 HRS	—

Countries

India

Contacts

Public ContactVISHAKHA TANWAR

MAHATMA GANDHI MEDICAL COLLEGE AND HOSPITAL

drvishnugarg7686@gmail.com9252067445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026