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A study to assess the effectiveness of topical application of urea lactic acid ointment versus coconut oil for prevention of hand foot syndrome in patients of solid tumor associated with chemotherapy in tertiary care hospital

A Comparative study to assess the effectiveness of topical application of urea lactic acid ointment versus coconut oil for prevention of hand foot syndrome among patients receiving anti VEGF-TKI for solid tumor at Medical Oncology, OPD, PGIMER, Chandigarh (2021-23)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044477
Enrollment
70
Registered
2022-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C228- Malignant neoplasm of liver, primary, unspecified as to type

Interventions

Intervention1: coconut oil: topical application of coconut oil will be apply thrice a day, quantity will be 1 tbsp for hand and 2 tbsp for foot Control Intervention1: urea lactic acid: topical applica

Sponsors

National institute of Nursing EducationPGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to participate in study Patients receiving anti-VEGF TKI

Exclusion criteria

Exclusion criteria: Pre-existing hand-foot syndrome at the time of enrollment

Design outcomes

Primary

MeasureTime frame
Decrease in the incidence of a hand-foot syndrome associated with tyrosine kinase inhibitorTimepoint: 15 DAYS, 30 DAYS, 45 DAYS, AND 60 DAYS AFTER INTIATION OF CHEMOTHERAPY—

Secondary

MeasureTime frame
To compare the effectiveness of urea lactic acid vs coconut oil in prevention of hand-foot syndrome associated with tyrosine kinase inhibitorTimepoint: 15 days, 30days, 45 days and 60 days—

Countries

India

Contacts

Public ContactMrs Shruti

National Institute of Nursing Education, PGIMER

shruti2011pgi@gmail.com8437748011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026