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Comparing effect of two drugs that is Clonidine and Fentanyl on adding along with Spinal drug in spinal anaesthesia

A COMPARITIVE STUDY OF CLONIDINE AND FENTANYL AS ADJUVANT TO BUPIVACAINE 0.5% HEAVY IN SPINAL ANAESTHESIA FOR LOWER LIMB SURGERIES

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044473
Enrollment
60
Registered
2022-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: clonidine: Clonidine apparently produces its sedative and anaesthetic-sparing effects by stimulation of centrally located alpha2 adrenoceptors. Analgesia seems to be mediated ma

Sponsors

Nil
Lead Sponsor
Basaveshwar Teaching and General Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: American Society Of Anaesthesiologist (ASA) grade I & II Age between 18-60years Patients undergoing elective lower limb surgeries

Exclusion criteria

Exclusion criteria: Pregnancy Patients with spinal deformities Patients with allergy to study drug Subjects having any absolute contraindications for spinal anaesthesia like raised intracranial pressure, severe hypovolemia, bleeding diathesis, local infection

Design outcomes

Primary

MeasureTime frame
To study the onset , duration of sensory and motor blockade of the drugs under study To Compare Clonidine and Fentanyl as Adjuvant to Heavy Bupivacaine 0.5% in Spinal Anaesthesia in subjects undergoing for lower limb surgeriesTimepoint: Level of blockade and vital parameters to be assessed from time of injection of spinal anaesthesia upto 6hours—

Secondary

MeasureTime frame
To Study the Adverse effects of drugs under studyTimepoint: From time of injection to 24hours of time—

Countries

India

Contacts

Public ContactDr Ekanth S

Mahadevappa Rampure Medical College

gajendra.glb@gmail.com9886252233

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026