study to compare the effect of oral pregabalin(pain killer) and oral paracetamol(pain killer) as pain relief after operation in patients undergoing leg surgeries under spinal anaesthesia

Prospective randomized control study of comparison of efficacy of oral pregabalin and oral paracetamol as pre-emptive analgesics in patients receiving spinal anaesthesia for lower limb surgery

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044462

Enrollment

Registered

2022-07-29

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: pregabalin: patients will be given Tablet Pregabalin 140mg orally 1 hour before the surgery Control Intervention1: Tablet Paracetamol: patients will be given Tablet Paracetamol 1 gm ora

Eligibility

Inclusion criteria

Inclusion criteria: 1)all patients giving consent 2)patients undergoing lower limb surgeries 3)ASA grade I and II

Exclusion criteria

Exclusion criteria: Uncooperative and unwilling patients hypersensitivity to drug history of neurological and seizure disorder surgeries lasting for more than 3 hours

Design outcomes

Primary

Measure	Time frame
to find out which analgesic is better in postoperative patients undergoing lower limb surgeries under spinal anaesthesiaTimepoint: post operative 0 hours to 12 hours	—

Secondary

Measure	Time frame
to find out when the first rescue analgesic was given in patients post operatively and at what time period post operativeTimepoint: post operative 0 hours to 12 hours	—

Countries

India

Contacts

Public ContactDr Raghbir Singh Gehdoo

Dr D Y Patil school of medicine

disha.saxenaaa@gmail.com8698562596

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026