Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
Intervention1: Dexmedetomidine: Intranasal administration of dexmedetomidine at a dose of 1 micrograms/kg body weight 45 minutes prior to induction
Control Intervention1: 0.9 % normal saline: Intrana
Sponsors
Kidwai memorial institute of oncology
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged between 18 to 65 years belonging to ASA status 1 ad 2 with BMI between 18 -25 kgm2 undergoing surgery under general anesthesia
Exclusion criteria
Exclusion criteria: Patient refusal. Patient with known nasal pathology. History of allergy to study drug or other anesthetic agents.patient with history ischemic heart disease, cerebrovascular accident, or cardiovascular disease. Patient with second or third degree heart blocks. Patients on long term sedatives or anxiolytics. Patients on Anti hypertensive like clonidine, beta blockers, alpha methyl dopa, alpha adrenergic agonists.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic responses to laryngoscopy and intubationTimepoint: 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation, anxioysisTimepoint: 45 minutes | — |
Countries
India
Contacts
Public ContactDr Namrata Ranganath
Kidwai memorial institute of oncology
Outcome results
None listed