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To observe acute confusional state in paediatric patients following recovery from general anaesthesia by comparing two different methods of induction of anaesthesia.

A randomised control study to compare two different methods of induction of anaesthesia in paediatric patients and its effect on emergence delirium.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044425
Enrollment
60
Registered
2022-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine: 2 mg/kg till the loss of Eyelash Reflex. Control Intervention1: Sevoflurane: Induction with 8 % and 100% Oxygen till the loss of Eyelash Reflex.

Sponsors

Krishna Institute of Medical Sciences Deemed To Be University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Child with ASA PHYSICAL STATUS 1 and 2 of either Sex. 2) Age 2 to 12 years.

Exclusion criteria

Exclusion criteria: 1) Known allergies to the drugs used. 2) Child belonging to ASA III and above. 3) Child with a history of any Cardiovascular, respiratory, or central nervous system disorder. 4) Child with Neurological diseases, developmental delay, Airway difficulty.

Design outcomes

Primary

MeasureTime frame
1) To measure and compare the incidence of agitation and delirium in paediatric patients after the recovery (i.e., after the discontinuation of anaesthesia) between two methods of induction of anaesthesia, IV induction with Ketamine and Inhalational induction with Sevoflurane using paediatric anaesthesia emergence delirium score.Timepoint: To access the Emergence Delirium in the Paediatric Patients using Paediatric Anaesthesia Emergence Delirium Score at 0, 15, 30, 60 and 120 mins.

Secondary

MeasureTime frame
1. To assess the ease of mask acceptance. 2. To compare the hemodynamic response between both the types of induction of anaesthesia. Timepoint: 1. To assess the ease of mask acceptance while inducing. 2. To compare the hemodynamic response between both the types of induction of anesthesia, After Intubation, 5 min, 10 min, 15 min, 20 min and 25 min.

Countries

India

Contacts

Public ContactVilas S Kapurkar

Krishna Institute of Medical Sciences "Deemed To Be University" ,Karad

vskapurkar@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026