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The efficacy of lower doses of Lasers when exposed on an periodontal intra bony defect may produce regenerative effects

Evaluation Of The Regenerative Potential Of Low Level Laser Therapy In The Management Of Intra-Bony Defects Associated With Chronic Periodontitis Patients â?? An Ex-Vivo And In-Vivo Study.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044413
Enrollment
64
Registered
2022-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Low Level Laser Therapy: Use of Low Level Laser Settings using AMD Picasso Soft tissue Diode Laser Dose : 2j/cm2 frequency route : irradiation with non contact mode without activation t

Sponsors

Dr PSG Prakash
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with Probing pocket depth >=5 mm and Clinical attachment loss of >= 3 mm. 2) Patients with 2 walled or 3 walled intrabony defects, with defect depth of >= 3 mm. 3) Full-mouth plaque score (FMPS) 4) Full-mouth bleeding score (FMBS) 5) Patients who are systemically healthy; with no disease that will have a bearing on the outcome of the surgical intervention

Exclusion criteria

Exclusion criteria: 1) Patients diagnosed with malalignment of teeth at the defect site. 2) Patients with systemic disease or drugs that contraindicates periodontal surgery. 3) Patients with history of smoking and pan chewing. 4) Sites with advanced furcation involvement. 5) Pregnant and lactating women 6) Patients who have under chemotherapy or radiotherapy. 7) Patients with parafunctional habits 8) Patients with crowns or bridges at the site of the defect. 9) Patients who have undergone Root Canal Treatment at the site of the defect.

Design outcomes

Primary

MeasureTime frame
Probing Pocket depth Clinical Attachment levels Radiographic Bone fillTimepoint: Baseline, 6 months, 1 year Baseline, 6 months, 1 year Baseline and 1 year

Secondary

MeasureTime frame
Osteogenic markers like RUNX2, Osteopontin and BMP-2 expression are to be evaluatedTimepoint: 3,7,14 days.

Countries

India

Contacts

Public ContactDr PSG Prakash

Department of Conservative Dentistry and Endodontics SRM Dental college ramapuram campus

kavithas1@srmist.edu.in9940048022

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026