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Effect of spinal Ropivacaine Heavy with or without Buprenorphine on after surgery pain in legs orthopaedic surgeries

Effect of Intrathecal Ropivacaine Heavy with or without Buprenorphine on postoperative analgesia in lower limb orthopaedic surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044406
Enrollment
50
Registered
2022-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Buprenorphine: After confirming free flow of clear cerebrospinal fluid, the cerebrospinal fluid will be aspirated slowly following which 50% of the 0.75% Ropivacaine Heavy 3ml (22.5 mi

Sponsors

sharda hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective lower limb orthopaedic surgeries under subarachnoid block. 2. ASA class I and II 3. Age 18-60 years 4. Height 150-170 cm 5. BMI 6. Both genders

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate in study 2. Infection at the site of injection of spinal anaesthesia 3. Patient having history of drug allergy to local anaesthetic and buprenorphine . 4. Patient having any deformities of the spine 5. Patient receiving steroids, analgesics and sedatives. 6. Patient with history of chronic pain. 7. Patient having history of endocrine, cardiovascular, renal or CNS disease. 8. Patient having history of bleeding disorder. 9. Patient having history of psychiatric disorders

Design outcomes

Primary

MeasureTime frame
To compare the duration of postoperative analgesia of Intrathecal Ropivacaine Heavy with or without Buprenorphine in lower limb orthopaedic surgeriesTimepoint: upto 24 hours—

Secondary

MeasureTime frame
To compare the effect of Intrathecal Ropivacaine Heavy with or without Buprenorphine on postoperative analgesia in lower limb orthopaedic surgeries with regard to: 1. Onset of sensory block and motor block 2. Duration of sensory block and motor block. 3. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and Mean arterial pressure (MAP) 4. Side effects (a) Nausea and vomiting (b) Urinary retention (c) Sedation (d) Respiratory depressionTimepoint: upto 24 hours—

Countries

India

Contacts

Public ContactDr Sharmistha Singha

school of medical sciences and research

uttam.verma@sharda.ac.in9968604211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026