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Use of a drug (norepinephrine) for prevention of fall in BP in pregnant patients posted for delivery with operation during spinal anaesthesia

Prophylactic norepinephrine infusion in preventing hypotension during spinal anaesthesia for caesarean delivery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044398
Enrollment
140
Registered
2022-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: Group A-Norepinephrine infusion: Prophylactic norepinephrine infusion started at 5 microgram/ml Control Intervention1: Group B-Normal saline infusion: Infusion of normal saline 5 microg

Sponsors

RNT Medical College and MB Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of anaesthesiologists physical status less than 3 Nonlaboring, Normotensive, Term and singleton pregnancy taken up for elective caesarean section under spinal anaesthesia like previous caesarean section, Breech presentation, Cephalopelvic disproportion, Pregnancy following infertility treatment, Cord round neck, Non progression of labour, Baseline systolic BP 90-140 mm Hg

Exclusion criteria

Exclusion criteria: Patient refusal, Emergency indication of caesarean section like antepartum haemorrhage, Fetal distress, Obstructed labour, Umbilical coed prolapse, Preeclampsia, Gestational diabetes, Essential hypertension, More than 2 previous lscs, History of PPH, Multiple gestation, Patients with associated systemic illness, History of seizures, Coma,neurological signs or Symptoms,any allergy to local anaesthetic agent, Weight 100kg Height 180cm.

Design outcomes

Primary

MeasureTime frame
Incidence of hypotension Timepoint: Intraoperatively till delivery of baby (30min)

Secondary

MeasureTime frame
Total norepinephrine consumption, Haemodynamic parameters, rescue doses of vasopressorTimepoint: Intraoperatively (1hr)

Countries

India

Contacts

Public ContactDr Chanchel Mary Thomas

RNT Medical College and MB Hospital

vbedimd@gmail.com9829025373

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026