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THE EFFECT OF INJECTABLE STEROID DURING ENDOSCOPIC THERAPY IN CORROSIVE (ACID OR ALKALI) ESOPHAGEAL STRICTURE (NARROWING)

“THE EFFECT OF INTRALESIONAL TRIAMCINOLONE IN PATIENTS OF CORROSIVE ESOPHAGEAL STRICTURE UNDERGOING ESOPHAGEAL BOUGIE DILATATION: A DOUBLE BLIND RANDOMIZED PLACEBO CONTROLLED TRIAL ?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044397
Enrollment
40
Registered
2022-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K222- Esophageal obstruction

Interventions

Intervention1: ENDOSCOPIC BOUGIE DILATATION OF CORROSIVE ESOPHAGEAL STRICTURE WITH INTRALESIONAL TRIAMCINOLONE KENACORT INJECTION: Before endoscopic esophageal dilation, patients will be sedated by in

Sponsors

AVISHEK BERA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of corrosive esophageal strictures aged above 18 years and below 60 years Presenting after at least 6 weeks of ingestion of corrosive substance Having single stricture in the esophagus Baseline Dysphagia score 1 or above Recurrent corrosive strictures Treatment experienced patients with prior episodes of esophageal bougie dilatation for corrosive esophageal stricture

Exclusion criteria

Exclusion criteria: Stricture within 25 cm from incisor teeth or Cricopharyngeal Stricture Number of strictures 2 or more Patients unable to abide by the follow up rule Postoperative case of corrosive stricture of esophagus excluding feeding jejunostomy for gastric outlet obstruction Patients not giving consent

Design outcomes

Primary

MeasureTime frame
To determine whether intralesional Triamcinolone injection reduces total number of esophageal dilatation in patients of corrosive esophageal stricture undergoing esophageal bougie dilatationTimepoint: 6 month—

Secondary

MeasureTime frame
To determine whether intralesional Triamcinolone affects the frequency of complication rate among two groups of the study population Timepoint: 6 month;To determine whether intralesional Triamcinolone affects the periodic dilatation index among two groups of the study population Timepoint: 6 month;To determine whether intralesional Triamcinolone decreases time to relief of dysphagia in patients of corrosive esophageal stricture undergoing esophageal bougie dilatation Timepoint: 6 month;To determine whether intralesional Triamcinolone injection increases the rate of successful endoscopic management of corrosive esophageal stricture defined as dysphagia free period of at least 6 month without endoscopic or surgical intervention Timepoint: 6 month—

Countries

India

Contacts

Public ContactDEBASHIS MISRA

IPGMER AND SSKM HOSPITAL

rajjoy5661@gmail.com9477371103

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026