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Comparison of lung expansion methods and standarad ventilator care without lung expansion methods on patient lung function, recovery and discharge from the ICU

Effect of mechanical ventilation and alveolar recruitment on post operative pulmonary complications and lung mechanics in patients - Undergoing cardiopulmonary bypass : A prospective interventional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044365
Enrollment
40
Registered
2022-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: I21A- Other type of myocardial infarction

Interventions

Intervention1: Alevolar recruitment maneuver: Repeated alveolar recruitment maneuvers are done using vital capacity maneuver ( pressure of 40cm of water for 10 sec ) after cross clamp release , after

Sponsors

Nizams institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) AGE >18years 2) Elective cardiac surgery 3) Surgical intervention performed with CPB, aortic cross-clamping 4) Valvular surgery, coronary surgery, surgery on the ascending aorta 5) Median sternotomy and bi-pulmonary ventilation

Exclusion criteria

Exclusion criteria: 1) Patient refusal 2) Non elective cardiac surgery 3) Previous cardiac surgery 4) Anticipated circulatory arrest. 5) Patients with BMI >30 6) Patients with end-stage chronic kidney disease (defined as need for dialysis) 7) Patients with known respiratory diseases (ongoing respiratory infections, asthma, COPD, OSAS) 8) Patients already intubated before arrival in operating theatre 9) Previous pulmonary resection 10) Patients with a preoperative oxygen saturation 45 mmHg 11) Patients with hepatic disease, defined as elevated liver enzymes (higher than two reference intervals) 12) Patients with pulmonary hypertension (defined as preoperative estimated systolic pulmonary artery pressure >55 mmHg)

Design outcomes

Primary

MeasureTime frame
To compare the changes in oxygenation in the form of PaO2/FiO2 , pulmonary compliance and haemodynamics in patient who have undergone recruitment maneuvers vs those who did notTimepoint: Primary outcome variables are noted after alveolar recruitment maneuvers after cross clamp release , after sternal closure and in the post operative period

Secondary

MeasureTime frame
1)To compare the changes in pulmonary compliance and haemodynamics 2)Time to extubation 3)Time to discharge from ICU 4)Pulmonary complications such as pneumonia , pleural effusion , pneumothoraxTimepoint: Secondary outcome variables are noted until the patient is discharged out of the ICU.

Countries

India

Contacts

Public ContactDr Bhuvana satya sesha sai paluri

Nizamâ??s institute of medical sciences

padmajanims@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026