Visual and X-ray changes following the use of calcium sulphate and blood platelet concentrates after placing implants immediatly in tooth extraction sockets

Effect of combination of platelet rich plasma with calcium sulfate on bone healing in immediate implants: A clinico-radiograhic study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044359

Enrollment

Registered

2022-07-26

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K081- Complete loss of teeth Health Condition 2: K027- Dental root caries Health Condition 3: K089- Disorder of teeth and supporting structures, unspecified Health Condition 4: K083- Retained dental root

Interventions

Intervention1: PRP and Calcium sulfate: o Prior to extraction, venous blood sample (10ml) will be aspirated for the reparation of PRP. o The calcium sulfate bone graft will be mixed with absolute alco

Eligibility

Inclusion criteria

Inclusion criteria: 1) Systemically healthy patients in the age of =18 years. 2) Tooth / teeth indicated for extraction and future prosthesis. 3) Good oral hygiene. 4) Tooth /teeth without labial bone defect. 5) Patients willing to participate with written informed consent.

Exclusion criteria

Exclusion criteria: 1) Systemic conditions / diseases contraindicating surgical Tooth/Teeth removal and implant placement. 2) Patients using smokeless as well as smoking form of tobacco. 3) Patients taking bone sparing agents or systemic medication that might affect bone metabolism. 4) Tooth/Teeth having periodontitis. 5) Pregnant and lactating females.

Design outcomes

Primary

Measure	Time frame
1. The width of buccal plate (horizontal dimensions) around implant at the crestal level, 3 mm and 6 mm from bone crest will be recorded on CBCT. 2. The distance between the implant shoulder and bone crest will be recorded as vertical dimensions on CBCT. 3. The gingival phenotype will be assessed with endodontic file on buccal surface of implant placed.Timepoint: Twice during the study period i.e. before extraction of tooth / teeth and implant placement (baseline), and 16 weeks post-operatively on CBCT	—

Measure

Time frame

1. The width of buccal plate (horizontal dimensions) around implant at the crestal level, 3 mm and 6 mm from bone crest will be recorded on CBCT. 2. The distance between the implant shoulder and bone crest will be recorded as vertical dimensions on CBCT. 3. The gingival phenotype will be assessed with endodontic file on buccal surface of implant placed.Timepoint: Twice during the study period i.e. before extraction of tooth / teeth and implant placement (baseline), and 16 weeks post-operatively on CBCT

—

Secondary

Measure	Time frame
The gingival phenotype will be assessed with endodontic file on buccal surface of implant placed.Timepoint: Twice during the study period i.e. before extraction of tooth / teeth and implant placement (baseline), and 16 weeks post-operatively on CBCT	—

Countries

India

Contacts

Public ContactRaghavendra Medikeri

maharashtra University of health sciences, Nashik

ajaybandal10@gmail.com9766337620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026