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To check the effect of intravenous dexmedetomidine versus dexmedetomidine in subarachnoid space on pain in patients undergoing surgery under spinal anaesthesia with heavy bupivacaine

A randomised controlled interventional study for analgesic effects of intrathecal versus intravenous dexmedetomidine on subarachnoid anesthesia with hyperbaric bupivacaine at SMS Medical College , Jaipur during 2021-2023

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044353
Enrollment
90
Registered
2022-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S869- Injury of unspecified muscle and tendon at lower leg level Health Condition 2: O- Medical and Surgical Health Condition 3: S828- Other fractures of lower leg

Interventions

Intervention1: Intrathecal versus intravenous dexmedetomidine: Group A- patient will receive iv 20ml 0.9%NaCl over 10 min f/b intrathecal 2.4ml 0.5% bupivacaine +0.2ml normal saline group B- patient w

Sponsors

Department of anesthesiology Sawai Man Singh medical College and attached hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 Patients scheduled for elective surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: Patient not willing to participate ASA grade 3 and 4 Cases with sepsis or infection on local site History of hypovolemia,anemia, compromised cardiac function Cases with raised intracranial tension History of alcohol abuse or opioid intake or sedative medication History of blood coagulopathies Patient allergic to drug used for study Uncooperative patient Failure of spinal anesthesia

Design outcomes

Primary

MeasureTime frame
Mean time duration of two segment regression Mean time duration of first dose of rescue analgesiaTimepoint: 24 hours

Secondary

MeasureTime frame
Total dose of rescue analgesia given in 24 hours Post operative period Mean time to reach highest sensory and motor blockade Timepoint: 24 hours postoperative period

Countries

India

Contacts

Public ContactDr Manu

Sawai Man Singh medical College and attached hospital

anupamag213@gmail.com9414240245

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026