To compare the effect of premedication on success of Local anesthesia in pulpal inflammation

To evaluate the efficacy of premedication with non steriodal anti-inflammatory drugs, corticosteriods and placebo on success of inferior alveolar nerve block in achieving pulpal anaesthesia in symptomatic irreversible pulpitis-A randomized control double blinded study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044351

Enrollment

100

Registered

2022-07-26

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R50-R69- General symptoms and signs Health Condition 2: K040- Pulpitis

Interventions

Intervention1: oral piroxicam Ketrolac Dt oral prednisolone oral dexamethasone : 20 mg oral piroxicam 10mg oral Ketrolac Dt 5 mg oral prednisolone 1 mg oral dexamethasone. The route of administr

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy individuals of age 19 to 45 2.Subjects participating in the study had first or second mandibular molar teeth with symptomatic irreversible pulpitis. 3.Patients with no systemic disease

Exclusion criteria

Exclusion criteria: 1.Patients who are allergic or sensitive to local anesthesia and drugs used in this study 2.Pregnant or lactating women 3.Patients who had taken any analgesic medication in the preceding 12 hours before the treatment. 4.Patients with history of peptic ulcer 6.Patients not willing to provide informed consent

Design outcomes

Primary

Measure	Time frame
To evaluate the success rate of Inferior alveolar nerve block with use of premedications.Timepoint: 1 hour	—

Secondary

Measure	Time frame
To evaluate the success rate of Inferior alveolar nerve block with use of premedications.Timepoint: at baseline	—

Countries

India

Contacts

Public ContactGeethanjali R

Karpaga vinayaga institute of dental sciences

madhu_endo@yahoo.com9962677450

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026