Health Condition 1: B968- Other specified bacterial agents as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: nil: nil
Control Intervention2: nil: nil
Control Intervention3: Prokineticin-2: The diagnostic and prognostic accuracy of Prokineticin-2 for sepsis in cr
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Patients having clinical features suggestive of sepsis as defined by Sepsis-3 definition (2016) at the time of ICU admission
Exclusion criteria
Exclusion criteria: Patients/ relatives who refused to give informed consent. Age less than 18 years. Patients with terminal stage of disease (malignancy , Acquired immunodeficiency Syndrome, end stage liver or renal disease). HIV/HBSAG/HCV . Autoimmune disorders/ metabolic diseases. On long term steroids/ immunosuppressants/ chemotherapy Osteoarthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare diagnostic and prognostic value of Prokineticin-2 and Procalcitonin in critically ill sepsis patientsTimepoint: Day 1, Day 7 or on day of discharge or death (whichever is earlier) and on day 28 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Ability of Prokineticin-2 to prognosticate the multi-organ failure in critically ill patients as assessed by SOFA scores. 2) To establish Prokineticin-2 as a predictor of outcome of sepsis in terms of 28 days mortality 3) To compare Prokineticin-2 vs Procalcitonin values as a predictor of outcome of sepsisTimepoint: Day 1, Day 7 or on the day of discharge or death (whichever is earlier) and on day 28 | — |
Countries
India
Contacts
Public ContactDr Kavyashree Bhat
All India Institute of Medical Sciences, Jodhpur
Outcome results
None listed