FindTrial
Sign In

Effects of Vitamin D on the cardiovascular autonomic functions of subjects who are working in High Altitude Areas, in excess of 15000ft, for 3 to 4 months. This study will shed light on the Autonomic Nervous System, a specialized system of nerves that has profound effects on Heart.

EFFECT OF VITAMIN D SUPPLEMENTATION ON CARDIOVASCULAR AUTONOMIC FUNCIONS IN SUBJECTS IN HIGH ALTITUDE : A RANDOMIZED CONTROL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044289
Enrollment
400
Registered
2022-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Vitamin D Supplementation: Vitamin D3 (10 micrograms)+ Calcium (500 mg) daily for 3 to 5 months depending upon duration of stay in high altitude Control Intervention1: Placebo: A placeb

Sponsors

DGAFMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy subjects who have been newly inducted to High Altitude areas (heights in excess of 9000 ft) and who will further proceed to locations at heights of more than 15000 ft.

Exclusion criteria

Exclusion criteria: Presence of Systemic Hypertension, any history of Respiratory and Cardiovascular illness, obese individuals with BMI more than 30, smokers and subjects taking any medications other than the Pharmacological Intervention for the Study

Design outcomes

Primary

MeasureTime frame
To compare the effects of Calcium + Vitamin D Supplementation with a Placebo in subjects sojourning to high altitude after 03 TO 05 months.Timepoint: 03 To 05 months—

Secondary

MeasureTime frame
To estimate Vitamin D levels in the serum of subjects prior to induction to heights of more than 15000 ft and post de-induction after a period of stay for 3 to 5 months, to assess the Cardiovascular Autonomic Functions in the same group of subjects prior to induction to heights of more than 15000 ft and post de-induction after a period of stay for 3 to 5 months. Timepoint: 03 TO 05 months—

Countries

India

Contacts

Public ContactLt Col Dr Razzakur Rahman

High Altitude Medical Research Centre

razzakur1@gmail.com9401771078

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026