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how decrease in basic ions in body identify the chance of having kidney dysfunction in patients having infection

Alactic Base excess, A bedside early prediction tool for sepsis associated Acute kidney injury. A prospective observational study - ABE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/07/044168
Enrollment
200
Registered
2022-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A418- Other specified sepsis

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

IMS and SUM hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18 to 60years 2. ICU patients suspected to be having sepsis as per sepsis-3 definition.7 (Increase in SOFA Score by 2 from SOFA score at admission to ICU)

Exclusion criteria

Exclusion criteria: 1. Patients having ESRD/CKD. ( From Radiological evidence, USG KUB done as per routine ICU protocol in all suspected septic patients in ICU) 2. Patients who are on propofol infusion ( >4mg/kg/hr for > 48hrs) and Metformin ( >3gm per day for at least 6 months) 3. Acute coronary syndrome 4. A known case of Chronic liver disease 5. Patients previously admitted in other ICUs and wards 6. RRT performed for Non renal causes

Design outcomes

Primary

MeasureTime frame
To predict sepsis associated AKI in ICU patients within 24hours of sepsis diagnosis from different Alactic base excess values.Timepoint: 24hrs, 48hrs, 72hrs and 1 week

Secondary

MeasureTime frame
To do a subgroup analysis for predicting risk of AKI among patients having different range of Alactic base excess valuesTimepoint: 24hrs, 48hrs, 72hrs and 1 week

Countries

India

Contacts

Public ContactDr Sanghamitra Mishra

IMS & SUM HOPSITAL

hod.ccm.ims@soa.ac.in8847867034

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026