Comparing pain and anxiety after lignocaine and articaine administration under general anesthesia in children

Evaluation of pain and anxiety using lignocaine and articaine in children undergoing full mouth rehabilitation under general anaesthesia: a randomised controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044144

Enrollment

Registered

2022-07-19

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Articaine: 4% Articaine with vasoconstrictor 1:20000) in carpule of Septodont brand. Administered once intraoperatively. Dose depends on weight of child. Control Intervention1: 2% Ligno

Eligibility

Inclusion criteria

Inclusion criteria: def/DMFT greater than 4 ASA classification of 1 Children indicated for treatment under general anesthesia COVID-19 negative

Exclusion criteria

Exclusion criteria: Known allergy to lignocaine or articaine Underlying systemic condition Children with special needs Any respiratory tract infection

Design outcomes

Primary

Measure	Time frame
Pain Salivary amylase levelsTimepoint: Pre treatment 3 hours and 6 hours post treatment	—

Secondary

Measure	Time frame
Intra-operative vitals (Heart rate, end tidal carbon dioxide, SPO2)Timepoint: Intraoperatively during pulpectomy of lower molar during access opening, cleaning and shaping and obturation of tooth.	—

Countries

India

Contacts

Public ContactVignesh R

Saveetha Dental College and Hospitals

palakjaniani@gmail.com9820775554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026