Level of salivary biomarkers before and after myofunctional treatment

Salivary C-reactive protein levels in children with class II malocclusion and sleep disorders - before and after myofunctional therapy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044126

Enrollment

Registered

2022-07-19

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K14- Diseases of oral cavity and salivary glands Health Condition 2: J989- Respiratory disorder, unspecified

Interventions

Intervention1: Myofunctional therapy: Selection of children with class II malocclusion who need Myofunctional therapy with minimal duration for 9 months. Eg. Twin block appliance, etc Control Interven

Eligibility

Inclusion criteria

Inclusion criteria: Children with Sleep disorders and Class II malocclusion who need myofunctional appliance

Exclusion criteria

Exclusion criteria: -Children with obesity (BMI > 95th percentile for age and gender).21 -Children with asthma and chronic upper respiratory disorder. -Children with diabetes or pre-diabetes. -Children with acute infections. -Children with any genetic abnormality or underlying systemic disease. -Children with cerebral palsy or neuromuscular diseases. -Children with prior history of sleep apnea treatment with continuous positive airway pressure (CPAP) or oral appliances/orthodontic treatment. -Children with mouth breathing habit.

Design outcomes

Primary

Measure	Time frame
Changes in level of salivary biomarkersTimepoint: 9 months	—

Secondary

Measure	Time frame
Changes in level of salivary biomarkersTimepoint: 9 months	—

Countries

India

Contacts

Public ContactDr Trupti Bhosale

ABSMIDS

docvabitha29@gmail.com9448770874

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026