Health Condition 1: E669- Obesity, unspecified
Conditions
Interventions
Intervention1: Weight bearing and structured resistance exercises with nutritional intervention: Structured resistance exercise: Initially all the exercises will be demonstrated by a trained physiothe
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: -Age 30-60 years -BMI>=25 Kg/m2 -Willing to give consent to participate in the study
Exclusion criteria
Exclusion criteria: -Known or recently diagnosed diabetes mellitus (HbA1c>=6.5%) or coronary heart disease -Contraindication to aerobic exercise or progressive resistance training -Any severe acute or chronic illness, severe end organ dysfunction, post organ transplant -Known malignancy, HIV/ HBsAg/Anti HCV positivity -Chronic alcohol use ( >30 g/day in men and >20 g/day in women) or any other drug abuse -Use of any medications that may affect the muscle function or mass such as corticosteroids, anabolic steroids, protein supplements, performance enhancing medications etc. -Pregnancy and lactation, any physical deformity or loss of extremity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Impact of combination of nutritional intervention along with progressive resistance training and weight bearing exercise on bone mineral density and muscle mass, strength and function in osteosarcopenic individualsTimepoint: Muscle strength and function will be assessed at baseline, 3 months and at 6 months of intervention Muscle mass and bone mineral density will be assessed at baseline and at 6 months of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of weight bearing and resistance exercise training and nutritional interventions on metabolic parameters, bone resorption and bone formation biomarkers in obese osteosarcopenic individualsTimepoint: Assessment of metabolic parameters will be assessed at baseline, 3 month and at 6 month Assessment of bone resorption and bone formation biomarkers will be done at baseline and at 6 month;Prevalence and risk factors of osteosarcopenia among obese individuals.Timepoint: Risk factors of osteosarcopenia will be assessed at baseline and prevalence will be assessed when desired number of osteosarcopenia patients will be recruited over 26 months. | — |
Countries
India
Contacts
Public ContactDr Ranveer Singh Jadon
AIIMS, New Delhi
Outcome results
None listed