A study to compare action of Dashamoolakatutreyam Kashaya Granules and Simhyadi Kashaya Granules in the management of Tamaka Shwasa (Bronchial Asthma)

An open labelled, active controlled, randomized, comparative clinical study to evaluate the efficacy of Dashamoolakatutreyam Kashaya Granules and Simhyadi Kashaya Granules in the management of Tamaka Shwasa with special reference to Bronchial Asthma

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044108

Enrollment

120

Registered

2022-07-18

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J452- Mild intermittent asthma Health Condition 2: J453- Mild persistent asthma Health Condition 3: J454- Moderate persistent asthma

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of age group 18 to 60 years irrespective of gender, occupation, and socio-economic status will be selected for the study. 2) Patients who are conscious and well oriented. 3) Patients in Avegakala Avastha. 4) Patient presenting with Pratyatma Lakshanas of Tamaka Shwasa. 5) Patient presenting with Clinical Features of Bronchial Asthma. 6) FEV1 or PEF 60-80% and = 80% predicted (GINA Guidelines)

Exclusion criteria

Exclusion criteria: 1) Immunocompromised patients, 2) patients with acute exacerbation of Bronchial Asthma, 3) Acute Infections of Respiratory System requiring other treatments, 4) Patients of tuberculosis. 5) Uncontrolled Diabetes Mellitus, 6) patients who are on immunosuppression treatment for any other disease. 7) History of Cardio-vascular Diseases, 8) Uncontrolled Hypertension. 9) Pregnant woman and lactating mother. 10) FEV1 or PEF = 60% (GINA Guidelines)

Design outcomes

Primary

Measure	Time frame
Marked changes in PEFR and FEV1 (as assessed by Spirometry)Timepoint: Day – 1, Day- 15,Day- 30,Day- 45,Day- 60,Day- 75,Day- 90	—

Secondary

Measure	Time frame
Gurguruka (wheezing), Swasa- Khichrata (dyspnea), Kasa (cough), Ura-Parshva Pidana (chest tightness), Nidra (sleep disturbances) Timepoint: Day – 1, Day- 15, Day- 30,Day- 45,Day- 60,Day- 75,Day- 90;Reduction in Days with wheeze marked changes will be noted in Days of slowed down or discontinued physical activities due to asthma Nights awaken due to asthma Unscheduled hospital visit due to asthma reduction in Number of asthma exacerbations.Timepoint: Day – 1, Day- 15, Day- 30,Day- 45,Day- 60,Day- 75,Day- 90	—

Measure

Time frame

Gurguruka (wheezing), Swasa- Khichrata (dyspnea), Kasa (cough), Ura-Parshva Pidana (chest tightness), Nidra (sleep disturbances) Timepoint: Day – 1, Day- 15, Day- 30,Day- 45,Day- 60,Day- 75,Day- 90;Reduction in Days with wheeze marked changes will be noted in Days of slowed down or discontinued physical activities due to asthma Nights awaken due to asthma Unscheduled hospital visit due to asthma reduction in Number of asthma exacerbations.Timepoint: Day – 1, Day- 15, Day- 30,Day- 45,Day- 60,Day- 75,Day- 90

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Countries

India

Contacts

Public ContactDr Nicy Wilson W

Parul Institute of Ayurved

shailesh.deshpande260036@paruluniversity.ac.in9763104451

Outcome results