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The effect of usual versus limited fluid therapy in children undergoing abdominal, chest and genitourinary surgery.

The effect of standard versus restricted fluid therapy in pediatric patients undergoing major elective abdominal, thoracic and genitourinary surgery: a non-blinded randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044087
Enrollment
60
Registered
2022-07-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q442- Atresia of bile ducts Health Condition 2: Q391- Atresia of esophagus with tracheo-esophageal fistula Health Condition 3: D350- Benign neoplasm of adrenal gland Health Condition 4: D126- Benign neoplasm of colon, unspecified Health Condition 5: D152- Benign neoplasm of mediastinum Health Condition 6: D157- Benign neoplasm of other specifiedintrathoracic organs Health Condition 7: K835- Biliary cyst Health Condition 8: K900- Celiac disease Health Condition 9: Q444- Choled

Interventions

Intervention1: Restricted fluid therapy: During intra-operative period, restricted fluid therapy group will receive maintenance and deficit correction as per Holliday-Segar formula and blood loss repl

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with parental consent 2.Age between 1 year and 10 years 3.ASA 1 & 2 patients 4.Major elective surgery- abdominal, thoracic and genitourinary open surgery

Exclusion criteria

Exclusion criteria: 1.Patients with electrolyte imbalances 2.Patients with altered hemodynamic status 3.Surgery duration

Design outcomes

Primary

MeasureTime frame
1.Postoperative hypernatremia 2.Rise in serum lactate 3.Rise in blood urea 4.Rise in serum creatinine Timepoint: At the end of surgery

Secondary

MeasureTime frame
1.Signs of fluid overload 2.Postoperative nausea and vomiting 3.Postoperative weight gain 4.Difference in amount of intraoperative fluid given in both the groups 5.Duration of hospital stay 6.Any delayed increase in blood urea and serum creatinine on post-operative day 2 Timepoint: At the postoperative period upto the discharge of the patient.

Countries

India

Contacts

Public ContactVignesh S

AIIMS

rashmiramachandran1@gmail.com9868397812

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026