To compare post operative pain relief of combination of two drugs (intraperitoneal irrigation of bupivacaine plus hydrocortisone) vs one drug (bupivacaine alone) in patients undergoing laparoscopic surgery for removal of gall bladder.

A comparative study of impact on Post-operative analgesia with intraperitoneal irrigation of high volume low concentration bupivacaine plus hydrocortisone vs bupivacaine alone in patients undergoing elective cholecystectomy.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044059

Enrollment

Registered

2022-07-15

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: High Volume low concentration Bupivacaine with Hydrocortisone: Intraperitoneal irrigation of High Volume low concentration Bupivacaine with Hydrocortisone as a form of post op analgesia

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are willing to give written informed consent. Patients with ASA Grade 1 and 2. Patients scheduled for elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. PATIENT REFUSAL 2. ALLERGY TO LOCAL ANESTHETIC DRUGS 3. PATIENTS WITH ACUTE PANCREATITIS,CHRONIC PAIN, CHOLEDOCHOLITHIASIS 4. PATIENTS WITH CHRONIC OPIOID USE, CHRONIC NSAID USE 5. INABILITY TO COMPREHEND VAS 6. PATIENTS WITH CONVERSION OF LAPAROSCOPIC CHOLECYSTECTOMY TO OPEN CHOLECYSTECTOMY.

Design outcomes

Primary

Measure	Time frame
Time to first rescue analgesicTimepoint: Time to first rescue analgesic	—

Secondary

Measure	Time frame
incidence of shoulder painTimepoint: first 48 hours;Time to AmbulationTimepoint: First 24 hours;Total episodes of vomitingTimepoint: first 24 hours;Total rescue analgesic requirementTimepoint: first 24 hours	—

Countries

India

Contacts

Public ContactAji Khan

BMCRI

divyashukla17sep@gmail.com9945659167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026