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Pre and post surgery Ultrasound Doppler derived Renal Resistive index to predict kidney injury after liver transplant surgery.

Perioperative Doppler derived Renal Resistive Index (RRI) as a predictor of Acute Kidney Injury (AKI) after Living Donor Liver Transplantation (LDLT). A prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/07/044056
Enrollment
70
Registered
2022-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K745- Biliary cirrhosis, unspecified Health Condition 2: K740- Hepatic fibrosis Health Condition 3: K746- Other and unspecified cirrhosis ofliver Health Condition 4: K743- Primary biliary cirrhosis Health Condition 5: K744- Secondary biliary cirrhosis

Interventions

None listed

Sponsors

Institue of Liver and Biliary Sciences ILBS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 18 to 65 years who will be undergoing Living Donor Liver Transplantation in Institute of Liver and Biliary sciences during the study period.

Exclusion criteria

Exclusion criteria: patient refusal, acute liver failure patients undergoing liver transplant, patients with pre-op Hepatorenal syndrome or Acute Kidney Injury in last 7 days or chronic renal failure, patients with renal artery stenosis, refractory ascites, patients undergoing redo-LDLT for graft failure and patients with poor echogenicity - inability to view kidney by ultrasound.

Design outcomes

Primary

MeasureTime frame
To determine whether preoperative and elevated postoperative Renal Resistive Index (RRI) predicts the post liver transplant Acute Kidney InjuryTimepoint: Renal Resistive Index will be done on the day before surgery and on post-operative day 1 and 2. patient will be followed up upto 14 days for any development of AKI.—

Secondary

MeasureTime frame
To study the effect of MELD Na score, duration of surgery, duration of warm and cold ischaemia time, blood loss and transfusion, amaount and type of fluid replacement, duration of IVC cross clamp, post reperfusion syndrome on the incidence of AKI. To find the incidence of AKI following liver transplant. To assess the ability of percentage RI to predict postoperative AKI. To determine the cut off value of postoperative RRI to predict AKI. TO find the inter-observer variablity of RRITimepoint: 14 days—

Countries

India

Contacts

Public ContactDr Saravanan M

Institute of Liver and Biliary Sciences

shivalipanwar@gmail.com9818241779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026