FindTrial
Sign In

A clinical trial to study how safe is a lazer treatment procedure and its effects on patients with dryness of eyes.

A clinical study to evaluate the safety and efficacy of Intense Pulse Light (IPL) therapy in evaporative dry eye disease by comparison of dry eye parameters and indices pre and post therapy.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/044052
Enrollment
75
Registered
2022-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H018- Other specified inflammations of eyelid

Interventions

Intervention1: Intense Pulse Light Therapy: A laser therapy that emits high intensity polychromatic light that acts on targetted ocular structures and causes photothermolysis and supression of inflamm

Sponsors

Suhani Dhar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.18-year-old and above 2. Diagnosed with moderate to severe MGD according to previously reported diagnostic criteria comprising of ocular signs and symptoms along with various tests such as Fluorescein Tear Film Break-up Time (FTBUT) and Schirmerâ??s Test. 3. Ocular Surface Disease Index Score (ODSI) in both eyes. 4. Obstruction of MG orifices observed under slit lamp examination. 5. Presenting at least two clinical signs: redness or thickening of the lid margin, telangiectasia, reduced or no secretions, poor quality secretions, and Meibomian gland capping 6. Willing to complete the three treatments and follow up regularly.

Exclusion criteria

Exclusion criteria: 1. Dermatosis or disorders of eyes and face. 2. Ocular surgery or trauma in last 3 months, 3. Active intraocular inflammation, allergy or infection 4. Eye lid structural abnormality. 5. Skin cancer or pigmented lesion in treatment zone. 6. Pregnancy and lactation

Design outcomes

Primary

MeasureTime frame
To evaluate the safety and efficacy of Intense Pulse Light Therapy in patients of evaporative dry eye diseaseTimepoint: Baseline, 15 days, 1 month and 3 months—

Secondary

MeasureTime frame
To assess the various dry eye parameters and indices in patients of Evaporative Dry Eye Disease receiving Intense Pulse Light ( IPL) therapy, before and after the therapy.Timepoint: TEAR MENISCUS NON-INVASIVE BREAKUP TIME (NIBUT) LIPID LAYER THICKNESS (LLT) MEIBOMIAN GLAND LOSS UPPER LID LOWER LID—

Countries

India

Contacts

Public ContactSuhani Dhar

Centre for Sight

drmahipal@gmail.com8876476444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026