Evaluation of the antimicrobial and clinical potency of copper nanoparticles gel against chlorhexidine gel after scaling and root planing (SRP) as a local drug delivery agent in patients with periodontitis.

To Assess and compare antimorobial and clinical efficacy of copper nanoparticles Gel with scaling and root planning against chldrhexidinegel with scaling and root planning as a local drug delivery agent in patients with periodontitis â??A randomized interventional study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/044047

Enrollment

Registered

2022-07-15

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Copper nanoparticle gel: Cu NPs exhibits excellent antiviral behavior as found to inactivate virus through inhibiting its RNA replication while its protein shell remained intact, which

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects should have at least 20 natural teeth. 2. Patients diagnosed with Generalized Periodontitis Stage 2 Grade B currently unstable without any risk factor (2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions) 3. Patients ready to give informed consent and ready to collaborate with the study protocol

Exclusion criteria

Exclusion criteria: 1. Pregnant/lactating mothers 2. Smokers/tobacco in any form 3. Patients who have undergone periodontal therapy, antibiotic or antiseptic therapy 6 months former to the study 4. Patients with bleeding disorders or under immunosuppressive chemotherapy 5. Any other systemic disease which can alter the course of periodontal disease

Design outcomes

Primary

Measure	Time frame
Papillary Bleeding Index (PBI) by Saxer and MuhlemannTimepoint: Baseline, 1 month and 3 months	—

Secondary

Measure	Time frame
Clinical attachment loss (CAL).Timepoint: Baseline, 1 month and 3 months;Modified Plaque Index (MPI) by Turesky et al modification of Quigley-Hein IndexTimepoint: Baseline, 1 month and 3 months;Probing pocket depth (PPD),Timepoint: Baseline, 1 month and 3 months	—

Countries

India

Contacts

Public ContactDr Prasad Dhadse

Sharad Pawar Dental College And Hospital

drprasaddhadse@gmail.com9822689401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026