Health Condition 1: I229- Subsequent ST elevation (STEMI) myocardial infarction of unspecified site
Conditions
Interventions
Intervention1: Angioplasty: Not using contrast during the angioplasty procedure
Sponsors
The madras medical mission
Eligibility
Inclusion criteria
Inclusion criteria: All consecutive patients, at high risk of developing CI-AKI (Mehran’s score >10) and undergo PCI will be randomized .
Exclusion criteria
Exclusion criteria: ST elevation myocardial infarction patients who will undergo primary PCI Chronic total occlusion Not willing to give consent for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The composite cardio-renal outcome at one-year post PCI will be compared between the zero-contrast PCI and standard of care PCI groups using Kaplan-meier survival analysis. Log rank test will be used to analyze the statistical significance. Kaplan-meier survival analysis will be done separately for ITT and per protocol populations. The individual events also will be compared using log rank test. Timepoint: One year | — |
Secondary
| Measure | Time frame |
|---|---|
| Defined as increase in serum creatinine by 0.3 mg/dl within 48 hours or Increase in serum creatinine to 1.5 times baseline, which is known or presumed to have occurred within the prior 7 days or urine volume less than 0.5 ml/kg/hour for 6 hours.7Timepoint: BASELINE one month and one year | — |
Countries
India
Contacts
Public ContactDr Nandhakumar Vasudevan
The madras medical mission
Outcome results
None listed