Health Condition 1: S069- Unspecified intracranial injury
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 3 month to 16 years 2. Hospitalized for a clinical indication like altered sensorium, seizures, amnesia, repeated vomiting, bleeding nose or Ear, skull fracture, or neurological signs after traumatic brain injury
Exclusion criteria
Exclusion criteria: 1. Patients who succumb within first 48 hours of hospitalization 2. Patients with pre-existing endocrinal disorder unrelated to existing illness 3. Patients with previously diagnosed static or progressive central nervous system disease (like epilepsy, brain tumor, meningoencephalitis, cerebral palsy) 4. Patients with history of consumption of drugs in the last 12 months which can affect interpretation of pituitary hormone levels (example corticosteroids, anti-epileptic drugs) 5. Patients with any major congenital anomalies (example neural tube defects) or chromosomal disorders 6. Patients who discontinue treatment before discharge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of pituitary disorders in children with traumatic brain injuryTimepoint: Baseline, 6 months, 12 months, 24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Association of pituitary dysfunction with the injury characteristics (severity, type, mechanism) b. Association of pituitary dysfunction with neuronal injury biomarkers c. Resolution of pituitary dysfunction in diagnosed cases during the study period Timepoint: 6, 12 and 24 months | — |
Countries
India
Contacts
Public ContactAashima Dabas
Maulana Azad Medical College
Outcome results
None listed