Skip to content

prevention of muscle twitching of etomidate by dexmedetomidine different doses

To study the effect of three different doses of dexmedetomidine as a premedication on the severity of etomidate induced myoclonus

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043998
Enrollment
90
Registered
2022-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Premedication with different doses of Dexmedetomidine and induction with etomidate: To study the effects of premedication with Dexmedetomidine on Severity and duration of myoclonus ind

Sponsors

SGRDIMSAR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who fall in Grade I and II of American Society of Anesthesiology (ASA). 2. Hemodynamically stable.

Exclusion criteria

Exclusion criteria: 1. Patients with adrenal cortex dysfunction, neurologic disease like epilepsy, psychiatric disorders. 2. Allergy to dexmedetomidine and etomidate. 3. History of Uncontrolled hypertension, bradycardia, heart blocks, heart failure. 4. Pregnancy.

Design outcomes

Primary

MeasureTime frame
To compare the effect of three different doses of dexmedetomidine as a premedication on the severity and duration of etomidate induced myoclonus.Timepoint: From the time after giving etomidate till the next 2 mins, severity of myoclonus will be noted

Secondary

MeasureTime frame
To compare the hemodynamic effect of three different doses of dexmedetomidine as a premedication after induction with etomidate induced myoclonus and their adverse effects.Timepoint: From the start of premedication till the end of surgery

Countries

India

Contacts

Public ContactDr Ketki Kaushal

SGRDIMSAR

kumarianitadr1@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026