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Use of Helmet Non-invasive ventilation Mask in Respiratory Failure

To study the effect of helmet Continuous Positive Airway Pressure Ventilation on oxygenation in semi-prone position in patients of mild to moderate ARDS: a prospective single arm non-inferiority trial - HOPE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043962
Enrollment
60
Registered
2022-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

Intervention1: Helmet CPAP: Helmet CPAP in semi-prone and prone position for 30 min to 2 hrs. Control Intervention1: not applicable: not applicable

Sponsors

PGIMS rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with age >=18 years 2. Patients with ARDS with PO2:FiO2 of 150-300

Exclusion criteria

Exclusion criteria: 1.Pregnancy 2.Patients with hemodynamic instability defined as requiring vasopressor support (i.e., a systolic blood pressure 3.Patients with altered sensorium or Glasgow Coma Scale (GCS) of less than 12 4.Patients with need of emergency intubation 5.Patients with Tracheostomy 6.Patients with upper airway obstruction 7.Patients with pH 50 mm of Hg in initial arterial blood gas analysis 8.Patients with pneumothorax on chest Xray. 9.Inability to reposition self for comfort without assistance 10.Spinal instability 11.Glaucoma or other condition with acutely elevated intraocular pressure

Design outcomes

Primary

MeasureTime frame
1.To assess the improvement in P/F ratio in semi-prone position in comparison to supine positionTimepoint: baseline, 30min to 2hrs during intervention and 30min after intervention

Secondary

MeasureTime frame
1. To compare the improvement in P/F ratio in Semi-prone and prone position in comparison to supine position. 2. To assess change in P/F ratio, ROX index and respiratory rate 30min to 1 hour after supination from semi prone and prone position. 3. To determine patientâ??s comfort in semi-prone and prone position in comparison to supine position. Timepoint: baseline, 30min to 2hrs during intervention and 30min after intervention

Countries

India

Contacts

Public ContactAman Ahuja

PGIMS

dhruvachaudhry@yahoo.co.in9991101616

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026