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RIF STUDY

The predictors of Incidence, Reinfection and Severity of disease in a cohort of SARS-CoV-2 antibody positive cases - A Prospective study - RIF ICMR

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/07/043960
Enrollment
9350
Registered
2022-07-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals aged >=5 years with IgG antibody positive for SARS-CoV-2 irrespective of their prior positivity by RT-PCR, Rapid Antigen Test, TruNat, CBNAAT.

Exclusion criteria

Exclusion criteria: Any contraindication to venipuncture

Design outcomes

Primary

MeasureTime frame
1. Incidence of microbiologically confirmed COVID-19 disease among previously seropositive participants. 2. Proportion of study participants with various genetic variants 3. Risk factors for development of Covid-19 infection and reinfection. 4. Factors associated with time to reinfection 5. Severity of symptoms in reinfection cases 6. High-risk population subgroups 7. Predictors of clinical severity of COVID-19 reinfection 8. Proportion of individuals getting reinfection Timepoint: 1. Incidence of microbiologically confirmed COVID-19 disease among previously seropositive participants. 2. Proportion of study participants with various genetic variants 3. Risk factors for development of Covid-19 infection and reinfection. 4. Factors associated with time to reinfection 5. Severity of symptoms in reinfection cases 6. High-risk population subgroups 7. Predictors of clinical severity of COVID-19 reinfection 8. Proportion of individuals getting reinfection

Secondary

MeasureTime frame
1. Proportion of vaccinated with reinfection 2. Proportion of vaccinated individual getting seroconverted Timepoint: 1. Proportion of vaccinated with reinfection 2. Proportion of vaccinated individual getting seroconverted

Countries

India

Contacts

Public ContactAmod Laxmikant Borle

Maulana Azad Medical College

dramodborle@rediffmail.com8393935207

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026