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Comparison of Fentanyl-Lignocaine versus Dexmedetomidine-Lignocaine nebulisation in awake fibreoptic nasal intubation.

A comparative study between Fentanyl-Lignocaine and Dexmedetomidine-Lignocaine nebulisation in awake fibreoptic nasal intubation

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043953
Enrollment
66
Registered
2022-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Nebulisation with Dexmedetomidine with Lignocaine in awake nasal fibreoptic intubation: Patient will be nebulised with Dexmedetomidine 1 microgram/kg with 4ml of 4% Lignocaine Interve

Sponsors

Dr Asmita Gupta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients giving written consent Patients of either sex Patients belonging to ASA grade I and II Patients with anticipated difficult intubation

Exclusion criteria

Exclusion criteria: Patient refusal. Patient with pregnancy, known alcoholic or drug abuser, or on chronic opioid therapy. Patient belonging to ASA grade IiII and above. Patients having hypersensitive reaction to drugs involved in the study. Patients with bradycardia, any atrioventricular block, heart failure, having significant neurological, hepatic,renal, and pulmonary disease. Patients undergoing emergency surgeries. Patients with psychiatric illness. Contraindication for nasal intubation like thrombocytopenia or coagulopathies.

Design outcomes

Primary

MeasureTime frame
To determine better nebulising agent to blunt airway reflexes during awake fibreoptic nasal intubationTimepoint: 3 minutes

Secondary

MeasureTime frame
To determine which interventional drug will ensure: Stable hemodynamics without respiratory depression during awake fibreoptic intubation Adequate patient cooperation Smooth intubating conditions (incidence of cough reflex, laryngospasm, gag reflex.Timepoint: 5 minutes

Countries

India

Contacts

Public ContactDr Ravi Prakash

King George medical university

raviprakash@kgmcindia.edu7897496901

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026