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A study of effectiveness of local application of insulin versus normal saline dressing in diabetic foot ulcer healing.

A study of effectiveness of topical insulin application in healing of diabetic ulcer wounds.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043952
Enrollment
50
Registered
2022-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications

Interventions

Intervention1: Insulin: Soluble human insulin (Human actrapid) injection of 40 IU/ml concentration. 1 IU of Insulin is applied for every square centimetre of wound area locally over the wound once a d

Sponsors

Kethineni Poojith
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Type 2 Diabetes Mellitus patients with ulcer for more than 3 weeks duration.

Exclusion criteria

Exclusion criteria: Chronic non healing wounds of other aetiology like osteomyelitis, vascular impairment.

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is to compare the effect of topical insulin versus normal saline on diabetic ulcer healing.Timepoint: At baseline, 4 weeks—

Secondary

MeasureTime frame
To check safety of topical insulin application in terms of any systemic absorption from the wound leading to hypoglycaemia.Timepoint: At baseline—

Countries

India

Contacts

Public ContactKethineni Poojith

Sri Ramachandra Institute of Higher Education and Research

naveenalexander@yahoo.co.in9949422622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026