Health Condition 1: N179- Acute kidney failure, unspecified
Conditions
Interventions
Intervention1: Sodium Profiling: Dialysate sodium will be adjusted as per profile 3 of Fresenius HD Machine
Control Intervention1: Standard Dialysate Sodium: Dialysis fluid sodium will be kept at 136m
Sponsors
KEM Hospital Pune
Eligibility
Inclusion criteria
Inclusion criteria: Acute kidney injury which needs renal replacement therapy Circulatory Shock which requires one pressor & requires ultrafiltration Mean arterial pressure (MAP) of at least 70 mmHg at the start of SLED
Exclusion criteria
Exclusion criteria: 1. Known chronic kidney disease or shrunken kidneys on ultrasonography 2. Chronic kidney disease dialyzed before 3. Had received oral antihypertensives within 24 hours of onset of shock 4. Current Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of hypotensive episodesTimepoint: one dialysis session | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of pre and post SLED blood pressure, MAP (mean arterial pressure) and VDI (Vasopressor dependency index)Timepoint: 1 dialysis session;Duration of SLED per sessionTimepoint: 7 days;ICU length of stayTimepoint: 1 month;Individual pressor requirement pre and post sessionTimepoint: one dialysis session;Serum Sodium levels pre & post SLEDTimepoint: one dialysis session | — |
Countries
India
Contacts
Public ContactShubhangi Humbre
KEM Hospital, Pune
Outcome results
None listed