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Comparative analysis in dose requirement of propofol for induction of anaesthesia at varying time intervals after fentanyl administration - a Randomized clinical trial

Comparative study of requirement of propofol for induction of anaesthesia with varying time intervals between fentanyl and propofol administration– a Randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043932
Enrollment
108
Registered
2022-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Propofol infusion, 5 min after Fentanyl administration : propofol infusion at 300 ml/hr 5 mins after Fentanyl administration while communicating verbally with the patient and will note

Sponsors

Chettinad Hospital and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Adult patients aged between 18 and 65 years 2) ASA-I & II physical status 3) Elective procedures under general anaesthesia

Exclusion criteria

Exclusion criteria: 1) Patient not willing to be in the study group 2) Contraindication to GA 3) ASA-III & IV physical status 4) BMI > 35 kg/m2 5) Anticipated difficult airway 6) Pregnant patients 7) History of allergy to study drug 8) Drug abuse including chronic alcoholics 9) Emergency procedures

Design outcomes

Primary

MeasureTime frame
To study the requirement of propofol for induction immediately, 5 and 7 mins after fentanyl administration Timepoint: At baseline, 4 weeks and 8 weeks

Secondary

MeasureTime frame
To compare the incidence of movement, vocalization and additional propofol requirementTimepoint: Soon after end of verbal response post induction

Countries

India

Contacts

Public ContactProf Dr Ashok Kulashekar

Chettinad Academy of Research and Education

ashokk_dr@yahoo.com9840498420

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026