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Assessing wound healing using MMP-8 levels in GCF of diabetic people with gum disease after LASER treatment with bone surgery

Assessment of wound healing using MMP-8 levels in GCF of diabetics with chronic periodontitis after diode laser assisted flap surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043898
Enrollment
30
Registered
2022-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Diode LASER assisted flap surgery: Patients fulfilling the inclusion criteria and giving consent will be selected, routine blood examinations and x- rays will be taken. Clinical parame

Sponsors

JSS Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group 30-50 years diagnosed with chronic periodontitis Patients with HbA1C within 8 Patients with at least 3 adjacent teeth in the same quadrant with a probing depth >= 5 mm, clinical attachment loss >= 6 mm, gingival index Patients with at least 20 natural teeth

Exclusion criteria

Exclusion criteria: Smokers Pregnant ladies and lactating mothers Use of antibiotics, steroidal or nonsteroidal anti-inflammatory drugs in the 6 months prior to the study Patients with other systemic conditions apart from diabetes Patients who require regenerative or resective procedures

Design outcomes

Primary

MeasureTime frame
At the end of the study, we expect a reduction in the Matrix Metalloproteinase-8 levels in Gingival Crevicular FluidTimepoint: Parameters will be assessed at baseline, 4 days, 7 days, and 3 months

Secondary

MeasureTime frame
Measuring clinical parameters before and after surgery to assess wound healingTimepoint: Clinical parameters will be measured at baseline (before surgery), 4th day after surgery, 7th day after surgery, and 3rd month after surgery

Countries

India

Contacts

Public ContactDr Kritika Banerjee

JSS Academy of Higher Education and Research

sheelagujjari@gmail.com9448836777

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 10, 2026