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Efficacy of Herbal medication in the reduction of microbial load of the root canal

Comparative evaluation of antibacterial efficacy of combination of Achyranthes aspera Linn and Trachyspermum ammi Linn, calcium hydroxide, and chlorhexidine as intracanal medicaments: A double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043862
Enrollment
40
Registered
2022-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

None listed

Sponsors

Dr Ram Surath Kumar K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with mature permanent maxillary central incisors, lateral incisors and canines with pulp necrosis, and asymptomatic apical periodontitis. 2) Patients above 18 years 3) Patients who are willing to give consent.

Exclusion criteria

Exclusion criteria: 1) Patients with calcified pulp chamber, periapical cyst, and contributory medical history. 2) Patients with any other systemic/psychological conditions, history of allergy reactions to the herbal medicaments or chlorhexidine, under medications such as anti-inflammatory drugs, antibiotics, and steroids within the past 3 months.

Design outcomes

Primary

MeasureTime frame
1) Reduction of Enterococcus faecalis count 2) Reduction of postoperative painTimepoint: Baseline, 7 days

Secondary

MeasureTime frame
Cost-effectivenessTimepoint: Baseline, 7 days

Countries

India

Contacts

Public ContactDr Anil V Ankola

KAHERs KLE VISHWANATH KATTI INSTITUTE OF DENTAL SCIENCES

ramsurathkumar1996@gmail.com9095066443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 5, 2026