Health Condition 1: K137- Other and unspecified lesions of oral mucosa
Conditions
Interventions
Intervention1: Topical Placentrex Gel (Albert David, India): 0.1g Placentrex Gel
twice daily topical application for 7 days, after laser depigmentation. (7 days)
Control Intervention1: No drug applied: Only laser depigmentation, with no post-operative application
Sponsors
Dr Shubhankar Mehrotra
Eligibility
Inclusion criteria
Inclusion criteria: 1. >18 years of age 2. Dummetâ??s Oral Pigmentation Index (DOPI) level: 1.5-3 3. Loeâ??s gingival index (GI) of 1 or less, and a plaque index (PI) of less than 10% 4. Patients with esthetic concern regarding smile 5. Absence of any systemic morbidities
Exclusion criteria
Exclusion criteria: 1. Severe periodontal disease 2. Current smokers 3. History of previous depigmentation procedures 4. Pathologic hyperpigmentation 5. Systemic disease that may affect wound healing (Diabetes)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Landrys Wound Healing Index (WHI)Timepoint: IMMEDIATELY AFTER PROCEDURE 3 DAYS POST OPERATIVELY 7 DAYS POST OPERATIVELY | — |
Secondary
| Measure | Time frame |
|---|---|
| Extent of epithelialization using Toluidine Blue StainingTimepoint: 3 days post operatively 7 days post operatively;Pain Perception (Visual Analog Scale)Timepoint: IMMEDIATELY AFTER PROCEDURE 3 DAYS POST OPERATIVELY 7 DAYS POST OPERATIVELY;Patient satisfaction using a pre-defined surveyTimepoint: IMMEDIATELY AFTER PROCEDURE 3 DAYS POST OPERATIVELY 7 DAYS POST OPERATIVELY | — |
Countries
India
Contacts
Public ContactShubhankar Mehrotra
Manipal College of Dental Sciences, Manipal
Outcome results
None listed