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Intraoperative fluid therapy in Neuroanesthesia

Intraoperative fluid therapy guided by pulse pressure variation versus Holliday Segar formula in elective craniotomies

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043843
Enrollment
100
Registered
2022-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: volume of fluid administered over approximately 5 hours: volume of fluid administered over approximately 5 hours Control Intervention1: Pulse pressure variation guided versus Holliday S

Sponsors

Shri Sathya Sai Institute of Higher Medical Sciences Bangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-60 2. Elective craniotomies 3. ASA II

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Patients who received intraoperative blood transfusion. 2. Patients with preoperative syndromes like DI/SIADH/CSW.

Design outcomes

Primary

MeasureTime frame
1. volume of intraoperative intravenous fluid infused. 2. presence of extravascular lung water. Timepoint: Immediate post operative period—

Secondary

MeasureTime frame
1. intraoperative hemodynamics. 2. arterial blood gas parameters. 3. capillary refill times Timepoint: immediate postoperative period—

Countries

India

Contacts

Public ContactVrushali Choudhary

SSSIHMS

choudhary.vrushali@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026