Health Condition 1: K135- Oral submucous fibrosis
Conditions
Interventions
Intervention1: Ayurvedic regimen for Group-I:: 1. Saptachhadadi Kashaya: Kavala (Gurgling) 15 ml twice daily
2. Irimedadi Taila: Local application with the help of cotton swab/ dropper- 5 ml twice da
Sponsors
CCRAS
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 years-60 years with OSMF are diagnosed clinically. 2. Patients who have not taken any treatment earlier for OSMF. 3. Patients who are ready to quit the habit of betel quid/ areca nut/ gutkha chewing and are willing for regular follow-ups.
Exclusion criteria
Exclusion criteria: 1. Extensive fibrosis with severe trismus with an inter incisal distance (IID) 2. Pregnant and lactating mothers. 3. Disease is most advanced with premalignant and malignant changes 4. Generalized fibromatosis 5. Oral manifestation of scleroderma 6. Oral lichen planus 7. Pale oral mucosa of anemia mimicking blanching 8. Chronic debilitating conditions such as DM, HT, HIV, etc. 9. Patients not willing to give up addiction habits of Gutka, Panâ??Masala, tobacco, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a.Relief/ changes in the clinical manifestation of OSMF (stomatitis, palpable fibrotic band, tongue protrusion and inter-incisal distance) Timepoint: Duration of treatment: Medication for 84 days (12 weeks) Follow up: 04 weeks without medication Total study Duration: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Changes in the real-time ultrasonography with high-frequency transducers, electromyography, and histopathological findings. b. Changes in the Quality of life of the patient Timepoint: baseline, and at the end of 84th day | — |
Countries
India
Contacts
Public ContactDr Kshirod Kumar Ratha
Central Ayurveda Research Institute, CCRAS, Bharatpur, Bhubaneswar. Khordha ORISSA 751029 India
Outcome results
None listed