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Effect of Two drugs infusion for postoperative analgesia in patients undergoing upper abdominal surgeries

Effect of epidural dexmedetomidine and fentanyl infusion for postoperative analgesia in patients undergoing upper abdominal surgeries: a randomised double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043764
Enrollment
68
Registered
2022-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K928- Other specified diseases of the digestive system

Interventions

Intervention1: postoperative pain using VAS score during rest and movement at different time postoperatively: Bupivacaine 0.1% 2 microgram/ml for 24 hrs at 6ml per hour fentanyl 24-48 hours Control

Sponsors

Department of Anaesthesiology
Lead Sponsor
Department of Anaesthesiology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patient of either gender of age between 18-65 years undergoing major upper abdominal cancer surgery and classified as American Society of Anesthesiologists (ASA) physical status class Iâ??III.

Exclusion criteria

Exclusion criteria: Age less than 18 year or more than 65 year. Patients with treatment of α-adrenergic antagonists History of arrhythmias, contraindications to placement of an epidural catheter (eg, coagulopathy, local infection, and vertebral anomalies), patients known to be allergic to bupivacaine, dexmedetomidine, or morphine, and patients treated with regular chronic pain medications. Non willing patents.

Design outcomes

Primary

MeasureTime frame
To compare the postoperative pain using VAS score during rest and movement at different time postoperativelyTimepoint: 4 weeks

Secondary

MeasureTime frame
To assess rescue analgesia, sedation score, intraoperative and postoperative hemodynamics, bowel recovery time, nausea and vomitingTimepoint: 48 hours

Countries

India

Contacts

Public ContactDr Reetu Verma

King Georges Medical University Lucknow

reetuverma1998@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026