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EFFICACY OF LOCALISED APPLICATION OF CRUSHED TRANEXEMIC ACID AND MEFENAMIC ACID TABLET COMBINATION IN POST EXTRACTION SOCKETS FOR CONTROL OF POST EXTRACTION BLEEDING AND REDUCTION IN PAIN AFTER EXTRACTION OF TOOTH

EFFICACY OF LOCALISED APPLICATION OF TRANEXEMIC ACID AND MEFENAMIC ACID TABLET COMBINATION IN EXTRACTION SOCKETS FOR CONTROL OF POST EXTRACTION BLEEDING AND PAIN

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043744
Enrollment
18
Registered
2022-07-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: TRANSET MF TABLET : Tranexemic acid:Mefenamic acid
500mg:250 mg Duration:applied only once immediately after extraction of tooth : TRANSET MF TABLET : Tranexemic acid:Mefenamic acid
500mg:250 mg LOCALISED APPLICATION OF 1/2 A TABLET IN EXTRACTION SOCKET ,LOCAL APPLICATION Duration:Applied only once immediately after extraction of tooth Control Intervention1: COMPARED TO NIL USAGE

Sponsors

DEVIKA J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Patients above 14 years of age • Patients who are medically fit • Patients with bilateral mandibular premolars indicated for orthodontic extractions one tooth on each side .

Exclusion criteria

Exclusion criteria: • Patients with uncontrolled diabetes • Past history of drug allergy,drug reactions • Pregnancy • Previous history of liver diseases and renal diseases • Patients with cardiac risks

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of localised application of tranexemic acid and mefenamic acid tablet combination in extraction sockets for control of post extraction bleeding. â?¢ To evaluate the efficacy of localised application of tranexemic acid and mefenamic acid tablet combination in extraction sockets for control of post extraction pain. â?¢ To evaluate the efficacy of localised application of tranexemic acid and mefenamic acid tablet combination in extraction sockets in wound healing and reducing the incidence of alveolar osteitis. Timepoint: ON THE DAY OF EXTRACTION:BLEEDING NOTED TILL PRIMARY HEMOSTASIS. PAIN SCALE NITED ON:1,2,3,7 DAYS . HEALING ON 7TH DAY—

Secondary

MeasureTime frame
To evaluate the efficacy of localised application of tranexemic acid and mefenamic acid tablet combination in extraction sockets for control of post extraction pain. â?¢ To evaluate the efficacy of localised application of tranexemic acid and mefenamic acid tablet combination in extraction sockets in wound healing and reducing the incidence of alveolar osteitis. Timepoint: PAIN SCALE NOTED ON:1,2,3,7 DAYS . HEALING ON 7TH DAY—

Countries

India

Contacts

Public ContactDevika

YENEPOYA DENTAL COLLEGE ,YENEPOYA UNIVERSITY

joycemathias26@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026