Health Condition 1: A499- Bacterial infection, unspecified
Conditions
Interventions
None listed
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Melioidosis: 1)Patients diagnosed with melioidosis only 2)No past history of receiving any melioidosis treatment 3)Above 18yrs of age 4)Patients with or without COVID-19 co-Infection Diabetes mellitus only: 1) Patients diagnosed with type-II diabetes mellitus 2) Patients on diabetes mellitus treatment Healthy controls: 1) Individuals with no history of diabetes mellitus 2)Above 18yrs of age
Exclusion criteria
Exclusion criteria: Melioidosis: 1) Patients with previous history of melioidosis 2) Patients with other co-infection 3) Relapse cases of melioidosis 4) Below 18yrs of age Diabetes mellitus only: 1) Patients with acute infection Healthy controls: 1) Individuals with no evidence of any active or chronic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of diabetes mellitus in Melioidosis patients with respect to its immunometabolismTimepoint: Outcomes will be measured at 0, 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| As the aim of the study involves understanding the effect of DM on cellular immunometabolic response of the melioidosis, it will offer insights into immunopathogenesis that might aid in identifying potential candidates for development of a vaccine and adjuvant therapies for people with DM for the susceptible population in the endemic areas or in identifying drug targets that may provide protection under diabetic co-morbidities.Timepoint: 10 years | — |
Countries
India
Contacts
Public ContactRanita Ghosh Dastidar
Kasturba Medical College, Manipal, MAHE
Outcome results
None listed