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THE EFFECTIVENESS OF CURCUMIN AND NON-CURCUMIN TOOTHPASTE FORMULATION ON GINGIVITIS AND PERIODONTITIS

A COMPARATIVE EVALUATION OF THE EFFECTIVENESS OF CURCUMIN AND NON-CURCUMIN TOOTHPASTE FORMULATION ON GINGIVITIS AND PERIODONTITIS â?? A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043703
Enrollment
60
Registered
2022-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: Z789- Other specified health status

Interventions

Intervention1: Group 1 - curcumin containing toothpaste. Group 2 - Non curcumin containing toothpaste.: brush teeth once a day for 30 days Control Intervention1: Toothpaste: Group 2 - Non-curcumin-con

Sponsors

ARUMUGAM P M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Patients aged between 25 - 60yrs. • All subjects having gingivitis and periodontitis with a probing pocket depth (PPD) of >3 mm. • All subjects should have at least 20 natural teeth. • All subjects need to have a plaque index of greater than 2 as measured by the Turesky et al. (1970) modification of the Quigley & Hein plaque index (1962). • All subjects need to be mentally stable. • Those who provide written informed consent will be included in the study. • No subjects should have undergone any dental treatment in the four-week period prior to the baseline examination.

Exclusion criteria

Exclusion criteria: • Those who are undergoing antibiotic or anti-inflammatory therapy or on medication for any underlying systemic disorders. • History of periodontal therapy in the past 6 months. • Inability to participate in the study for its entire duration. • Subjects with gross oral pathology are excluded. • Female subjects who are either pregnant or taking the contraceptive pill. • Subjects who have a history of known sensitivity or oral mucosal tissue reactions to the toothpaste.

Design outcomes

Primary

MeasureTime frame
reduction in overall bacterial load, bleeding on probing, plaque accumulation and periodontal pocketTimepoint: 7 months

Secondary

MeasureTime frame
reduction in bleeding on probing, plaque accumulation and periodontal pocketTimepoint: 7 months

Countries

India

Contacts

Public ContactARUMUGAM P M

Rajarajeswari dental college and hospital

yspkumar@gmail.com9901297908

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026