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Antihistamines for treatment of Long COVID

Antihistamines for treatment of Long COVID â?? A placebo controlled double blinded Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/07/043679
Enrollment
64
Registered
2022-07-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B338- Other specified viral diseases

Interventions

Intervention1: Loratadine 10 mg: Loratadine 10 mg once a day for 14 days Control Intervention1: Placebo: Placebo tablets once a day for 14 days

Sponsors

Dr Arjun M C
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults diagnosed with COVID-19 and presenting with Long COVID symptoms after 3 months of COVID-19 diagnosis (Diagnosed with RTPCR or RAT only)

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Patients who are severely ill, bedridden or cannot follow up in hospital Patients having Diagnosed Liver or kidney diseases Those who do not consent

Design outcomes

Primary

MeasureTime frame
Change in the intensity of symptoms after intervention. At baseline the symptoms will be recorded using a Binary (Yes/No) symptoms grid and at follow-up the same symptoms reassessed for change (Identical, worse, better, absent). Outcome will be reported as proportion of people who experienced change in symptoms. Timepoint: All participants will be followed up for a period of 14 days from the date of enrolment. Follow-up will be done telephonically.

Secondary

MeasureTime frame
Decrease in Chalder Fatigue scale score from baseline to follow-up Timepoint: All participants will be followed up for a period of 14 days from the date of enrolment. Follow-up will be done telephonically.

Countries

India

Contacts

Public ContactDr Arjun M C

St. Johns Research Institute

dr.arjun.aiims@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026