Identification of response of the nasal flora to Nasyakarma in sinusitis.

Identification of response of the nasal microbiota to Virechana Nasya in chronic rhinosinusitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/043644

Enrollment

Registered

2022-07-01

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J328- Other chronic sinusitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Nasya Arha 2. Age - Between 18 - 50 years, irrespective of gender. 3. Subjects presenting with two or more symptoms of (for more than 12 weeks) Nasal congestion Facial pain/pressure Anterior or posterior drainage Reduced or absent sense of smell

Exclusion criteria

Exclusion criteria: 1. Nasya Anarha 2. Subjects under antimicrobial therapy, undergone vaccination recently. 3. Subjects suffering from long standing debilitating illness.

Design outcomes

Primary

Measure	Time frame
To evaluate the changes in the nasal microbiota after Nasya Karma in CRS, by microbial culture of nasal swab sample of both the nostrilsTimepoint: The day before starting Nasyam, then on the 8th day the nasal swab sample culture would be analysed.	—

Secondary

Measure	Time frame
To assess the composition and load of the nasal microbiota before and after the Nasya Karma by analysis of the microbial culture of nasal swab sample of both nostrils. To propose a possible mechanism of action of the Nasya Karma on the nasal microbiome in CRS. Timepoint: Zeroth day, before starting the procedure and on the eighth day after the procedure	—

Countries

India

Contacts

Public ContactDr SHRUTHI SREEDHARAN

Amrita Vishwa Vidyapeetham

kpn@ay.amrita.edu9496096694

Outcome results