A new Innovative Oral Bioadhesive Formulation Incorporated With Nano Hydroxyapatite and Acorus Calamus Rhizome Extract To Enhance Remineralization of White Spot Lesions during braces Treatment â?? A Randomized Controlled Trial.

A NOVEL ORAL BIOADHESIVE FORMULATION INCORPORATED WITH NANO HYDROXYAPATITE AND ACORUS CALAMUS RHIZOME EXTRACT TO COMBAT WHITE SPOT LESION- A RANDOMIZED CONTROLLED TRIAL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/07/043628

Enrollment

Registered

2022-07-01

Start date

Unknown

Completion date

Unknown

Last updated

2022-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K026- Dental caries on smooth surface

Interventions

Intervention1: Bio adhesive placement during Orthodontic Treatment: 9-12 months Control Intervention1: Regular Orthodontic patients without any type of bioadhesive formulation.: 9-12 months

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects aged 18-25 years. 2. Healthy subjects with no other systemic diseases 3. Individuals undergoing fixed orthodontic treatment

Exclusion criteria

Exclusion criteria: 1. Subjects with systemic diseases 2. Individuals under any medication. 3. Individuals with high caries risk 4. Periodontally compromised individuals 5. Individuals unwilling to participate in the study

Design outcomes

Primary

Measure	Time frame
To prepare an oral bioadhesive formulation with the use of nano hydroxyl apatite and herbal extract separately and in combination To evaluate its efficacy in remineralization of white spot lesion.Timepoint: Total Duration of 18 months	—

Secondary

Measure	Time frame
To check the usability of Oral Bio adhesive for other than treating White spot lesionTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDr Jerusha T

JSS Dental College and Hospital

dr.suma@jssuni.edu.in8310099013

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026