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Does Dexamethasone and Lignocaine combination relieves Propofol induced pain effectively..?

Efficacy of Combination Intravenous Lignocaine and Dexamethasone on Propofol Injection-site Pain: A Randomized double blinded Clinical Trial in Adult Surgical Patients.

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/06/043601
Enrollment
104
Registered
2022-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DONE BY PRINCIPAL INVESTIGATOR: P. SEETHARAMA PRASAD: 104 patients, 18 to 75 years, ASA 1,2 & 3 posted for elective & emergency surgery under general anesthesia are selected, and divid

Sponsors

Pochinapeddi Seetharama Prasad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 18 & 75 years ASA grade 1,2 & 3 Elective & Emergency surgeries under G.A

Exclusion criteria

Exclusion criteria: Patients not willing to be in the study group, Pregnant patients Known allergy to study drugs Patients with neurological disorders Received analgesic medication Infection at the site of injection thrombophlebitis psychiatric disorders renal, hepatic, or cardiac problems

Design outcomes

Primary

MeasureTime frame
To evaluate the analgesic effect of dexamethasone,lignocaine alone or in combination in reducing the incidence of propofol injection pain. Timepoint: it is evaluated after 1 minute of injecting the study drug , and during the beginning of injection of propofol

Secondary

MeasureTime frame
To evaluate the severity of propofol injection site pain with Dexamethasone, Lignocaine alone or in combinationTimepoint: severity of propofol injection pain will be assessed at the end of the study approximate duration for total study 3 to 4 months

Countries

India

Contacts

Public ContactMerlin Shalini Ruth

Chettinad Hospital and research institute

merlin5shalini@gmail.com9790983957

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026